学历

研究生

学位

博士

研究方向

肿瘤与营养

所在学科

营养与食品卫生学

电子邮箱

m18744308309@163.com

简历

2010.09-2015.06

延边大学

预防医学/学士

2015.09-2021.03

韩国忠南大学

医学科学/硕、博士

2021.03-2021.08

韩国忠南大学

博士后

2022.03-至今

夜姑娘直播

讲师

获得项目

科研项目

1. 国家自然科学基金-青年科学基金项目，莱菔硫烷通过TLR6-PI3K信号轴靶向肿瘤相关巨噬细胞代谢抑制膀胱癌的机制研究（主持，202401-202612）

2. 夜姑娘直播人才科研启动项目，姜黄素通过重塑肠道菌群抑制食管癌作用的机制研究（主持，2022）

教学项目

1.健康中国战略下《营养与食品卫生学》“多元渗透式”思政教学改革与实践

发表文章

1. Jae Won Chang, Sung Tae Seo, Mi Ae Im, Ho-Ryun Won, Lihua Liu, Chan Oh, Yan Li Jin, Yudan Piao, Hae Jong Kim, Jung Tae Kim, Seung-Nam Jung, Bon Seok Koo. Claudin-1 mediates progression by regulating EMT through AMPK/TGF-β signaling in head and neck squamous cell carcinoma. Transl Res. 2022 Apr 21;S1931-5244(22)00071-8.

2. Seung-Nam Jung, Chan Oh, Jae Won Chang, Lihua Liu, Mi Ae Lim, Yan Li Jin, Yudan Piao, Hae Jong Kim, Ho-Ryun Won, Seong Eun Lee, Min Joung Lee, Jun Young Heo, Sangmi Jun, Doheon Lee, Woo Seok Kang, Dae-Woong Kim, Ki-Sang Rha, Young Il Kim, Yea Eun Kang, Bon Seok Koo. EGR1/GADD45α Activation by ROS of Non-Thermal Plasma Mediates Cell Death in Thyroid Carcinoma. Cancers (Basel). 2021 Jan 19;13(2):351.

3. Geonho Lee, Yea Eun Kang, Chan Oh, Lihua Liu, Yanli Jin, Mi Ae Lim, Ho-Ryun Won, Jae Won Chang, Bon Seok Koo. Neuropilin-2 promotes growth and progression of papillary thyroid cancer cells. Auris Nasus Larynx. 2020 Oct;47(5):870-880.

4. Yea Eun Kang, Jin Man Kim, Mi Ae Lim, Seong Eun Lee, Shinae Yi, Jung Tae Kim, Chan Oh, Lihua Liu, Yanli Jin, Seung-Nam Jung, Ho-Ryun Won, Jae Won Chang, Jeong Ho Lee, Hyun Jung Kim, Hyun Yong Koh, Sangmi Jun, Sun Wook Cho, Minho Shong, Bon Seok Koo. Growth Differentiation Factor 15 is a Cancer Cell-Induced Mitokine That Primes Thyroid Cancer Cells for Invasiveness. Thyroid. 2021 May;31(5):772-786.

5. Lihua Liu, Mi Ae Lim, Seung-Nam Jung, Chan Oh, Ho-Ryun Won, Yan Li Jin, Yudan Piao, Hae Jong Kim, Jae Won Chang, Bon Seok Koo. The effect of Curcumin on multi-level immune checkpoint blockade and T cell dysfunction in head and neck cancer. Phytomedicine. 2021 Nov; 92:153758.

6. Chan Oh, Ho-Ryun Won, Woo Seok Kang, Dae-Woong Kim, Seung-Nam Jung, Mi Ae Im, Lihua Liu, Yan Li Jin, Yudan Piao, Hae Jong Kim, Yea Eun Kang, Min Joung Lee, Jun Young Heo, Sangmi Jun, Nam Suk Sim, Jeong Ho Lee, Kunho Song, Young Il Kim, Jae Won Chang, Bon Seok Koo. Head and Neck Cancer Cell Death due to Mitochondrial Damage Induced by Reactive Oxygen Species from Nonthermal Plasma-Activated Media: Based on Transcriptomic Analysis. Oxid Med Cell Longev. 2021 Jul 6; 2021:9951712.

7.Seung-Nam Jung , Yea Eun Kang , Gun Ho Lee, Lihua Liu, Chan Oh, Yan Li Jin, Mi Ae Lim, Kyungmin Lee, Taejeong Oh, Ho-Ryun Won, Jae Won Chang, Bon Seok Koo. Brn3a/Pou4f1 Functions as a Tumor Suppressor by Targeting c-MET/STAT3 Signaling in Thyroid Cancer. J Clin Endocrinol Metab. 2020 Sep 1;105(9): dgaa316.

8. Kyungmin Lee, Jae Won Chang, Chan Oh, Lihua Liu, Seung-Nam Jung, Ho-Ryun Won, Young Il Kim, Ki-Sang Rha, Bon Seok Koo. HOXB5 acts as an oncogenic driver in head and neck squamous cell carcinoma via EGFR/Akt/Wnt/β-catenin signaling axis. Eur J Surg Oncol. 2020 Jun;46(6):1066-1073.

9. Lihua Liu, Chan Oh, Jae Hyung Heo, Hee Sung Park, Kyungmin Lee, Jae Won Chang, Seung-Nam Jung, Bon Seok Koo. Clinical significance of extrathyroidal extension according to primary tumor size in papillary thyroid carcinoma. Eur J Surg Oncol. 2018 Nov;44(11):1754-1759.

10. Lihua Liu, Seung-Nam Jung, Chan Oh, Kyungmin Lee, Ho-Ryun Won, Jae Won Chang, Jin Man Kim, Bon Seok Koo. LAMB3 is associated with disease progression and cisplatin cytotoxic sensitivity in head and neck squamous cell carcinoma. Eur J Surg Oncol. 2019 Mar;45(3):359-365.

11. Lihua Liu, Jae Won Chang, Seung-Nam Jung, Hee Sung Park, Taejeong Oh, Young Chang Lim, Bon Seok Koo. Clinical implications of the extent of BRAF V600E alleles in patients with papillary thyroid carcinoma. Oral Oncol. 2016 Nov; 62:72-77.

比赛获奖

202205，温州市合理膳食行动暨第一届中小学食育大赛小学组三等奖

202112，浙江省高校教师教育技术成果评比三等奖

荣誉及人才称号

2022年，夜姑娘直播优秀教育工作者